CAS NO: 1191237-69-0
Molecular weight: 291.26
Molecular formula: C12H13N5O4
Current content: HPLC99%
Product status: produce
Description: Density: Feline infectious peritonitis (FIP) is a devastating and almost always fatal feline disease that results from mutations in the common feline coronavirus (FECV), which infects 40-80% of cats worldwide. GS-441524, also known as GS-5734, is a potent inhibitor of the feline infectious peritonitis (FIP) virus. GS-441524 showed strong Chemicalbook inhibition on feline infectious peritonitis (FIP) virus. GS-441524 is a molecular precursor of pharmacologically active nucleoside triphosphate molecule. These analogues can be used as alternative substrates and RNA strand terminators for viral RNA-dependent RNA polymerase. GS-441524 has a non-toxic concentration of up to 100 in feline cells, effectively inhibits FIPV replication of CRFK cell cultures and a concentration of peritoneal macrophages as low as 1 in naturally infected cats.
